Cd36 pathway
WebCD36, a transmembrane glycoprotein (GP) that is also known as FA translocase (FAT), platelet GPIV, GP88, and scavenger receptor class B type 2 (SR-B2), is expressed on the cell surface in multiple cell types, … CD36 (cluster of differentiation 36), also known as platelet glycoprotein 4, fatty acid translocase (FAT), scavenger receptor class B member 3 (SCARB3), and glycoproteins 88 (GP88), IIIb (GPIIIB), or IV (GPIV) is a protein that in humans is encoded by the CD36 gene. The CD36 antigen is an integral … See more Primary In humans, rats and mice, CD36 consists of 472 amino acids with a predicted molecular weight of approximately 53,000 Da. However, CD36 is extensively glycosylated and … See more In humans, the gene is located on the long arm of chromosome 7 at band 11.2 (7q11.2 ) and is encoded by 15 exons that extend over more than 32 kilobases. Both the 5' and the 3' untranslated regions contain introns: the 5' with two and the 3' one. Exons 1, 2 and first … See more Malaria Infections with the human malaria parasite Plasmodium falciparum are characterized by sequestration of erythrocytes infected with mature forms of the parasite and CD36 has been shown to be a major sequestration … See more CD36 has been shown to interact with FYN. See more CD36 is found on platelets, erythrocytes, monocytes, differentiated adipocytes, skeletal muscle, mammary epithelial cells, spleen cells and some skin microdermal endothelial cells See more The protein itself belongs to the class B scavenger receptor family which includes receptors for selective cholesteryl ester uptake, scavenger receptor class B type I (SR-BI) and lysosomal integral membrane protein II (LIMP-II). CD36 interacts with … See more CD36 plays a role in the regulation of angiogenesis, which may be a therapeutic strategy for controlling the spread of cancer. Some data from in vitro and animal studies … See more
Cd36 pathway
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WebA selective inhibitor of Cdk5, (R)-DRF053, attenuated the AGE-induced Dil-ox-LDL uptake and CD36 gene expression, whereas anti-CD36 antibody inhibited the Dil-ox-LDL uptake but not Cdk5 gene expression. The present study suggests that AGEs may stimulate ox-LDL uptake into macrophages through the Cdk5–CD36 pathway via RAGE-mediated … WebSep 21, 2024 · We figure out the signaling pathway and the machineries required for the process, and identify dynamic palmitoylation of CD36 as a key regulatory mechanism. …
WebMar 31, 2016 · View Full Report Card. Fawn Creek Township is located in Kansas with a population of 1,618. Fawn Creek Township is in Montgomery County. Living in Fawn … WebTaken together, our study revealed that OPG signaling promotes liver steatosis through the ERK-PPAR-γ-CD36 pathway. The downregulation of OPG in NAFLD might be a compensatory response of the body to dampen excess hepatic fat accumulation in obesity. © 2024 by the American Diabetes Association. Publication types
WebCD36 facilitates the uptake of fatty acids by tumor cells, enhances lipid droplet (LD) development, and promotes the formation of acylcarnitine, monoacylglycerols, and other phospholipids [ 31 ]. It also facilitates fatty acid oxidation (FAO) [ 31 ]. The increase in fatty acid uptake hampers antigen presentation. WebSep 26, 2016 · CD36 is a scavenger receptor involved in fatty acid metabolism, innate immunity and angiogenesis. ... Otto, T. D. et al. Genome sequencing of chimpanzee malaria parasites reveals possible pathways ...
WebApr 4, 2024 · The authors further found HFD reduced the number of goblet cells, disturbed the mucin 2 secretion and thus LPS escapes the intestinal epithelial cells barrier via a transcellular pathway with the assistance of CD36.
WebMar 31, 2024 · CD36 regulates metabolic pathways of muscle energy 28. We stained RH-hMuSCs for CD82, CD54, CD36, CD47, CD90, CD73, and PDGFRα. Representative staining patterns for several of these markers are shown in Fig. 1D. The majority of cells expressed CD82 suggesting enrichment of stem cells. A small fraction of cells were … pearson order onlineWebCD36 is a class B scavenger receptor and structurally contains two transmembrane domains, which anchor a single, large, and heavily glycosylated extracellular loop. CD36 … meaning adhesiveWebApr 11, 2024 · Liver X receptor, pregnane X receptor, and peroxisome proliferator-activated receptor γ regulate CD36 [ 10 ]. Overexpression of enzymes and regulators involved in the lipid metabolic pathway has been reported in cancer, correlating with the clinical outcomes of cancer patients. meaning adhoc staffWebFeb 17, 2024 · Extended Data Fig. 4 CD36-deficiency results in a metabolic shift and elevated apoptosis in T reg cells. a, Indicated iT reg cells cultured in cancer cell-conditioned medium for 48 hrs (n=3 per... meaning adjunct professorWebSep 25, 2024 · Up-to-date, it is well known that CD36 increases FFA uptake and, in the liver, it drives hepatosteatosis onset and might contribute to its progression to NASH. Clinical studies have reinforced... pearson order stationeryWebJul 9, 2024 · CD36, a transmembrane glycoprotein (GP) that is also known as FA translocase (FAT), platelet GPIV, GP88, and scavenger receptor class B type 2 (SR-B2), … pearson ordering assessmentsmeaning admission