WebNational Center for Biotechnology Information Web节点无法启动、并显示"error:failure to build endpoint environment variables" 扩展/隐缩全局定位 节点无法启动、并显示"error:failure to build endpoint environment variables" 最后更新; 另存为PDF Views: 2 ...
National Center for Biotechnology Information
WebMar 27, 2024 · Time-lapse microscopy revealed that strong RNA interference (RNAi)-mediated silencing of KIF14 induced cytokinesis failure, causing several rounds of endoreduplication and resulting in multinucleated cells. Additionally, less efficacious KIF14-specific short interfering RNAs (siRNAs) induced multiple phenotypes, all of which … WebNov 28, 2024 · The most prominent and immediate consequence of cytokinesis failure is the formation of a tetraploid daughter cell with two centrosomes (Lacroix and Maddox, 2012). The tetraploid state is unstable and often develops into aneuploidy as a result of a continued cell cycle with more than two centrosomes, leading to the miss-segregation of … lithia service contract
Cfi-400945 Induces Cytokinesis Failure By Activating Hippo …
WebMay 24, 2010 · Cytokinesis failure at an early stage leads to multinucleation in HEK-293 and oral cancer cells. (a) Examples of successful and failed cytokinesis in UPCI:SCC103 cells as viewed by DIC optics ... WebMar 18, 2005 · The central spindle: a set of microtubule-based machines. Anaphase onset marks the beginning of cytokinesis. The proteolytic destruction of cyclins inactivates mitotic kinases and permits dephosphorylation and activation of several proteins that are critical for assembly of the central spindle, a set of antiparallel microtubules that become bundled … WebNov 2, 1998 · Such cells could arise as a result of cytokinesis failure in the first meiotic division, and failure of one of the centrosomes to separate in the second division. Cyclin … improved angelic halo