Web13 Jul 2024 · complex (CRL4 CRBN), 1 which promotes ubiquitylation and degradation of protein substrates, including IKZF1, IKZF3, and CK1 α . 2-4 Lenalidomide and thalidomide … WebThalidomide promotes degradation of SALL4, a transcription factor implicated in Duane Radial Ray Syndrome, part 6 Description Frequently used to treat morning sickness, the …
Thalidomide promotes degradation of SALL4, a …
Web20 Jan 2024 · Thalidomide and its derivatives induce protein degradation via the ubiquitin ligase cereblon (CRBN), and leading to teratogenic phenotypes during embryogenesis. … WebJustia Patents US Patent Application for DETECTION OF NOVEL DEGRADATION-RELATED INTERACTIONS Patent Application (Application #20240116707) DETECTION OF NOVEL DEGRADATION-RELATED INTERACTIONS . Dec 17, 2024. The present invention is related to a method for detecting and identifying protein-protein or protein-small molecule … machete latino
Thalidomide promotes degradation of SALL4, a transcription …
Web1 Aug 2024 · Thalidomide promotes degradation of SALL4, a transcription factor implicated in Duane Radial Ray syndrome. Katherine A Donovan Department of Cancer Biology, Dana … Web10 Aug 2024 · PXD010428 is an original dataset announced via ProteomeXchange. Dataset Summary Dataset History Publication List Donovan KA, An J, Nowak RP, Yuan JC, Fink EC, … Web3 Aug 2024 · One transcription factor, SALL4, is in charge of limb development and other parts of growth, and the degradation of SALL4 through Thalidomide causes deformed … machetel corinne